The problem of health maintenance has always been, and is still remaining to be, one of the most important and topical problems in biology and medicine. The results of epidemiologic observations and statistical analyses show slowering down of the progress in extending the life - span of the population of the Republic of Belarus and premature mortality of severe chronic infectious disease, such as heart diseases and malignant tumors. The majority of premature death cases among men and women is caused by either unbalanced nutrition or excessive consumption of fat and salt, or dietary selenium, potassium, calcium, nutrition fibre and vitamin deficiencies which reduce bodily adaptation capacities and stability towards the action of xenobiotics. The physiological antioxidant protection system, with selenium being a component, is stressed to the greatest extent. This is related to the fact that the population of many country's regions is exposed to low doses of ionizing radiation and dwells in areas characterized by increased heavy metal and other xenobiotic contents. The situation is aggravated by the territory of the Republic of Belarus being a bio- and geochemical region where the selenium levels are lower than the critical ones in soil (0.1 mg/kg) and not more than 10 ug/l in drinking water. Therefore the content of selenium, as a natural antioxidant, in foodstuffs and methods for selenium status improvement are of pivotal interest for the country. The average daily consumption as recommended by FAO must be 50-200 ug per day. Bread can be supplemented with selenium by adding the inorganic form (sodium selenite) directly during baking or by using bioselenium yeast, containing selenium as inorganic compounds (selenium methionine or selenium cysteine), in production of bread. Data are given on implementation of the selenium supplementation technology by different bakeries of the Republic of Belarus and Russian.