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The Effect of Anthocyanins on Accommodation in Visual Display Terminal Work

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The Effect of Anthocyanins on Accommodation in Visual Display Terminal Work

Introduction: As a healthcare professional, an optometrist should be able to instruct their patients on the best practice for vision problems. Therefore, the latest knowledge of the relieving vision problems also through nutrition should be known to optometrists.

Purpose: This thesis work aimed to determine whether anthocyanins, usually available from vegetables, influence ocular accommodation when burdened with visual display terminal (VDT) work. The systematic literature review investigated the connection between anthocyanin's impact on accommodation for VDT work compared to placebo.

Methods: This systematic literature review involved an analysis of 4 studies, and they were selected using PubMed, Ebsco, Elsevier and Google Scholar. The search was made on 21 March 2022 using English studies only. The publish date of records was limited to the years 2010–2022. Clinical studies for healthy subjects only were included in the literature review. All the studies were evaluated for critical appraisal using the Centre for Evidence-Based Medicine- University of Oxford evaluation sheets.

Results: The systematic review included four randomised controlled trials (RCTs) involving 271 participants. Used anthocyanin was derived from blueberry or maqui berry. The amount of used anthocyanin varied between 21-88,54 mg/day. In studies, the near vision was strained for at least 40 minutes. Three out of four studies indicated that anthocyanins reduced VDT load-associated eye fatigue, but none of the studies measured, for example, the amplitude of accommodation.

Conclusion: Understanding of accommodation requires a knowledge of the eye's biomechanics and physiology of the visual system. In conclusion, the systematic literature review failed to answer the research question. There is no golden standard for measuring accommodation, and RCTs included in the systematic literature review observed more eye fatigue than accommodation. However, accommodation difficulties can be one reason for eye fatigue. Based on the systematic literature review, there are indications that anthocyanins positively affect eye fatigue compared to placebo after VDT work. Due to their minor subjects, the result cannot be generalized. Also, the results cannot be considered clinically relevant due to the defects found in the studies. There is interest in the effect of anthocyanins on eye health and vision, so more robust evidence will be available in the future.

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