Intraocular pressure is formed by the aqueous humour secretion, circulation and outflow. The flow of the aqueous humor decreases as people get older. Millimeters of mercury, mmHg, is the unit in which the intraocular pressure is presented. Normal diurnal variation is between 11-21 mmHg and the average intraocular pressure is 16 mmHg.

This thesis is a research about the subject of daily intraocular pressure variation on a timeline of two weeks. The research consists of intraocular- and blood pressure measurements, the analyzation of the results and conclusion. This thesis also includes a theoretical part which explains the physiological effects on intraocular pressure.

Purpose of the research is to gather information about the daily variation of intraocular pressure on a healthy subject with some risk factors of glaucoma. Blood pressure has known to have an effect on intraocular eye pressure and was also measured in this research. Another reason for the research was that the researchers would learn more about intraocular pressure and its effect on the eye and that the researchers could use their gained knowledge on their upcoming careers.

Objective for the research was to gain credible and wholesome information about daily variations of intraocular pressure. Another objective was that the research would be a success, and the information gained could be used by the professionals already in the field and by students during their studies.

The research was performed in May 2017. The research was executed by measuring intraocular- and blood pressure variation on a daily basis for two weeks from a voluntary subject. The subject measured her intraocular pressure and blood pressure four times per day. The subject recorded the blood pressure and the time of the measurement herself. Blood pressure was measured with a sphygmomanometer which was calibrated before starting the research. Intraocular pressure was measured via Icare® HOME tonometer, which was borrowed from the Oulu University of Applied Sciences. Icare® HOME tonometer uses a sterilized single use probe to measure the pressure from the surface of the cornea. The probe has to be replaced after each measurement of both eyes. The probes were provided by Kahiko Oy. The measured intraocular pressure and the time of the measurement were registered to the tonometer automatically and the data was collected on the computer after the last measurement. The collected data was then embedded on an Excel-worksheet and different kinds of charts and diagrams were formed.